This gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined. [provided by RefSeq].
应用类型
WB, IHC
免疫原
PLA2G5
来源宿主
兔
反应性
人
保存建议
建议收到该Phospholipase A2, Group V (PLA2G5) Antibody产品后,储存温度为-20°C。避免重复冻融