该产品别称为6-Fluoro-3-hydroxypyrazine-2-carboxamide; CAS 259793-96-9; T-705,应用类型为:Neutralize,Favipiravir shows anti-influenza virus activities with IC50 ranged from 0.013 to 0.48 _g/ml for the influenza A viruses, from 0.039 to 0.089 _g/ml for the influenza B viruses, and from 0.030 to 0.057 _g/ml for the influenza C viruses. In mammalian cell lines (MDCK cells, Vero cells, HEL cells, A549 cells, HeLa cells, and HEp-2 cells), Favipiravir shows no cytotoxicity at concentrations up to 1,000 _g/ml. [1] In MDCK cells inoculated with seasonal influenza A (H1N1) viruses, Favipiravir induces lethal mutagenesis. [
产品描述
Favipiravir (T-705) is a novel viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5'-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with IC50
产品形式
干粉;灰白色粉末
保存建议
Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 1 month. Prevent multiple freeze-thaw cycles.